Study Finds Popular Cholesterol Drugs Vytorin, Zetia Not Effective

A recent study appearing in the New England Journal of Medicine has questioned the effectiveness of the popular cholesterol medication, Vytorin and its sister drug Zetia. Vytorin, a combination of Zetia and the generic drug Zocor, is the second most profitable pharmaceutical manufactured by Merck & Co. The Securities and Exchange Commission reports that sales of Vytorin and Zetia have raked in an astonishing $21 billion worldwide since 2003.

Although ezetimibe, the active ingredient in Vytorin and Zetia, has been shown to reduce cholesterol slightly, its ability to unclog coronary arteries is less than that of niacin, a cheap B vitamin, often available over the counter, according to the article. Additionally, Vytorin and Zetia competitors have been shown to prevent heart attacks, strokes and other cardiovascular diseases at a less expensive price tag, whereas Zetia and Vytorin have not been proven to do either, according to the study. In contrast to Lipitor, Zocor and other statin-type drugs which block cholesterol production in the Liver, Zetia prevents cholesterol absorption in the intestines. The difference between how the drugs reduce cholesterol has helped Zetia’s popularity, despite the fact its effectiveness has been questioned. Many patients have been prescribed Vytorin as an alternative to the unconfortable side effects of Niacin and other statins’ including liver problems.

This is the third study in the last two years that has cast doubt on the effectiveness of the pharmaceutical giant. Additionally, in August 2009, Merck and Schering-Plough agreed to pay $41.5 million to settle class-action lawsuits accusing the companies of withholding unfavorable information about the drugs. Due to their recent merge in Nov. 2009, both companies are responsible for the lawsuit. Vytorin has been linked to potentially harmful side effects, including a high rate of cancer deaths, according to a controversial study released in 2008.

These studies also question whether the Food and Drug Administration prematurely approved the drugs without requiring additional studies that illustrate the drugs’ effectiveness or ability to prevent heart attacks. Merck waited three years before starting a research study to examine the effect on heart attack rates among Zetia and Vytorin patients.

Additional studies will be conducted to further examine the effectiveness of the drugs, including heart attack prevention; however results are not expected to be available until at least 2012. Leading cardiologists have advised patients to use cholesterol drugs like Zetia and Vytorin only if his or her cholesterol levels have not improved with the use of other medications and life-style changes. Oftentimes, patients pursue a Vytorin lawsuit to seek monetary compensation to cover medical treatments due to cardiovascular complications.

Study Guides – Are They Helpful

Have you ever purchased a study guide that promises to teach you the the great and amazing study secret that no one has ever heard of? In most cases, this type of hype does not carry any real content or any fulfillment to the many promises they make. Hence, It will be my intention today to try to guide you on how to find out the real study techniques that lead to success in your studies. First of all, let me start out by this premise:

There are no real short cuts or secrets to gaining knowledge, it’s a matter of hard word and patience. Hence the saying: Patience might be sour but its result is sweet. Although there are no (or very few) real study secrets, there do exist certain study techniques that will make your studying a whole lot easier and even more effective. As you yourself might know, there are numerous ways of studying and I can’t compel you to choice a certain way that doesn’t fit you, hence I strongly urge you to do the following:

No matter how you learn the best (by visual experience, kinetic etc) make sure that you do not change horses in midstream concerning the way you learn, ie do not flip flop between different learning approaches. This will inevitable confuse you and may even worsen your study results in the long run. Remember that studying a small amount of information each day on a long time period is several times better than studying an immense amount of information over a short time frame. Contingency is a vital component in your studies, never forget that!

This article was not written in order to spell out all the thousands of different study techniques found under the sun but in the hope of making you realize that one can systemize the way one studies and that this change really can make a difference. Therefore, I urge you once again to sit down and reflect for a moment; how do you learn the best? Be sure to write down your answers and review them with your self and see if you can make any general conclusions, you might be stunned to see that you might have had a bad approach for too long.

Relationship Advice – 5 Ways To Open Your Heart & Connect With More Love

Are your chakras causing relationship problems? You may be thinking “chakra what?” And then doubly curious what it means to make your heart chakra happy. Many people are unaware of the chakra system that lives inside and guides us. Read on to learn more about how this system affects you and your relationship.

There are 7 chakras that run from the base of our spine to the crown of our head and are located a few inches in front of the spinal column. They cannot be seen physically, rather they are referred to as energy vortexes. They receive, assimilate and express our life force.

Relationship problems can arise when your chakras are out of whack because they interact with our psyche. If we have polluted thoughts these sites become clogged or stuck with this negative energy and get in the way of the natural flow of energy. This causes us to become out of alignment with who we really are.

In terms of love and romance, the heart chakra has to do with self-acceptance, self-love and the ability to love others. If you have unresolved pain from past issues of the heart or your current relationship is disappointing and less than luscious, you will find that you feel out of balance and the goal is to get back to a happy and healthy loving state.

You can ask yourself these three questions to figure out if your heart chakra needs some help:

1) Do you love yourself?
2) Are you able to forgive past hurts from others?
3) Do you blame yourself and others for all that’s wrong in your life?

If the answer is yes to any of the above then include these affirmations in your daily health regime:

1) “I am worthy of love”
2) “I release my pain and forgive the past. I am free to love.”
3) “I am loving to myself and others.”

Take action to improve your heart chakra by:

1) Singing.
2) Playing with a child or pet.
3) Taking a walk in nature.
4) Figuring out what brings you joy and happiness and doing it!
5) Phoning or spending time with someone you love.

Relationship problems are often caused by the stress our bodies and emotions are challenged with daily. Just like brushing your teeth, make it a ritual to take care of these energy vortexes to bring them back into harmonious alignment. Doing this on a regular basis ensures love and romance will always be yours.

The Missing Parent

I have four sons and a daughter. As my sons were growing up, they all did different adventures and trips with my husband. As adults the boys did an annual fishing trip with him and the fish stories began to grow like the hair on my sons’ faces! My boys will never forget those Dad times, especially since he passed away a few years ago.

The hard part about being the parent who is left is that those kinds of outings are hard to do with grown sons. It’s not like I’m the Dad figure who hunts and fishes and fixes car engines with them. I’m the Mom. I’m the cook or the comforter and all those other things Moms sometimes do.

When my sons start talking about their hunting expeditions or how they caught fish up in Canada or some other “manly” activity, I zone out! I start to think of things I want to paint or knit or sew. I don’t want to hear about where the deer got shot and how long they followed the blood trail. Ew! It’s like listening to what they did to the neighbor’s cat when they were little boys! (Believe me, you don’t want to know.)

So what’s a mom to do? Do I become a gun-toting hunter? Do I learn how to gut a deer or a fish without losing my cookies? Do I start wearing camo gear as my new fashion statement? What’s the answer to this challenge?

The way I have it figured is this-I am now officially a senior citizen, as much as I hate to admit it. I doubt I will become a licensed gun handler. I further doubt that I will ever enjoy processing deer meat or fish-I’d rather have an aquarium! So I’ll just fry your fish, cook your venison, and tell you when I hear a funny noise from your car. What do you say, boys?

Chilean Wedding Customs

Usually, in Chile, weddings go like this:

The man proposes and (so long as the lady accepts), he offers her an engagement ring which she places on her ring finger, just like in England and most of Europe.

Then they usually do alternate wedding ceremony rings and wear them on their proper ‘ring’ fingers.

Then, each time they set the marriage date, they have the Civil Service, which is the authorized aspect of things. This normally includes going to a Registry Office and having the authorized whys and wherefores read out in entrance of a few of your closest family and friends. That is when the couples transfer their wedding ceremony ring to the left ring finger in the event that they want. Plenty of Chileans put on their rings on their right ‘ring’ fingers too – it doesn’t matter to them. This service is then followed by an enormous dinner and a small occasion for aforementioned shut household and mates and a few presents are given.

The wedding takes place after some time (say, a month at the very least) after this authorized occasion. The wedding is a non secular ceremony. And a ceremony it definitely is.

You invite hundreds of individuals – from the furthest of your loved ones members and associates and their relations and pals, and your boss and their household and pals together – and squeeze them into the hugest and grandest church you will discover and afford. Then the wedding happens. The vows, the readings, the blessings from the priest and all other follows. Then they’ve a giant outdated band (yes, on the church ‘stage’) and a tremendous singer after which the bride and groom leave together to plenty of clapping and outside have a bit of rice throwing and images flashes, as is the norm in western cultures.

They’re then whisked away, followed by their guests, to a lavish celebration. Typically there are several hundred tables full with elaborate centerpieces with candles of their crystalline candle holders in every single place and flowers all around, twisted and twined by way of the chairs. Champagne is liberally handed out by tuxedo waiters as is caviar and pisco sours and different culinary and taste buddy delights, earlier than sitting right down to a full-service dinner. Throughout the reception, the groom, bride, and their dad and mom will cease by every table to say thank to their guests. The visitor in return, will give envelopes containing wedding ceremony cards and cash gifts (Chilean spurs was the standard wedding gifts within the olden days) to the newly wedded couples along with their blessing. Dinner is followed by an enormous Latino disco and a dancing party, which is opened by the groom and the bride’s first dance and the place everyone wears masks and has streamers and joke store child’s get together things. The social gathering does not recess until very late at night. The newly wedded couples then depart for his or her honeymoon.

The Five Main Components To Every Wedding Dress

There are basically five main components of every wedding gown. Those five components are: the silhouette, which helps shape the dress; the bodice, which helps to shape the waist; the neckline; the sleeves; and the train. Though there are many combinationss that help make wedding dresses unique, each dress contains these five parts. Lets take a deeper look at the main part, which is the silhouette.

The silhouette is the first thing that most people notice when they see a wedding dress. Thats because it sets the style for how people will view the rest of the dress. There are basically five silhouette styles that most wedding designers work with:

Ball Gown this is the most popular style of silhouette because it seems to enhance the bodies of most brides. It usually consists of a fitted bodice which helps make the waist look longer and thinner, yet highlights the breasts and hips, giving the appearance of an hour glass figure.

Empire Waist this is probably the second most popular silhouette style because it works to give women a waist that they might not have without this fitted style. Its known for having a fitted waist that leads to slimming, not flaring, skirt. This dress works well for both petite and full figured women.

Mermaid As more women are getting themselves in shape, the mermaid silhouette seems to be growing as the most popular wedding dress style. These dresses traditionally are form fitting to show off the natural curves of the bride, yet bursts out around the knees, reminding most people of the image of a mermaid. These women have to have the most confidence, because theres no hiding anything with this type of dress.

A-Line / Princess This style of wedding silhouetted dress can fit most body types because its meant to work with whatever body shape a woman has. Its not form fitting like the Mermaid, but usually has vertical lines and panels that help give a sleek, long look. Petite women will look taller in styles like this, and full figured women might look slimmer. However, its not usually recommended for women without defined waist lines.

Sheath This style of silhouette works well in a wedding dress for thin and petite women because it gives a form fitting look that can help give them more curves than they might normally have. Some women with hour glass figures will also like this style of dress. Petite women dont usually look good in these dresses, as they tend to make them look smaller than they naturally are.

Selecting the proper silhouette for your body type will go a long way towards making any wedding dress a spectacular success for any bride.

The Importance of Honesty in Online Dating

If you are serious about finding true love through online dating, its essential to look at the role of honesty and being truthful in your portrayal of yourself.

Your online profile should portray a flattering but accurate depiction of just who you are as a person. While you most certainly want to display your most attractive assets, you want to be sure you are being honest to potential dating partners. You want to help suitors get to know the real you. Being truthful is the best way to do this.

You dont and shouldnt- reveal every little thing about yourself. Part of the fun of online dating is the process of getting to know new people. But when it comes to what you look like and your lifestyle, these are things you want to be forthcoming about.

No woman likes to reveal her age after a certain point, but saying you are ten years younger than what you really are is not a good idea. People generally want to know approximately how old their romantic interests are. So if you are 60-ish, please dont say that you are 50-ish.

Physical appearance. Most people have things about themselves that they dont really love and they downplay this to their advantage. But if you are 50 pounds overweight, it wont help you in the long run to say you are slim and in shape. People who are interested in you want to get to know the real you. They will like you for who you really are.

Probably the number one reason that a promising online dating relationship fails is because one or both of the people were not being honest on their profile. Lying about age, marital status, appearance, children, or other things may seem like a good idea at first. And it may help you to feel more attractive. But when you actually take your dating to the next level and finally meet people in person, it will be hard to explain why you werent being truthful.

And think about if the roles were reversed. If you fell for someone online and developed a relationship, wouldnt you be upset or hurt if you found out that your date was not really who they said they were? If you fell for a single guy with no children, how would you feel if you found out he was divorced for the 3rd time and had 2 adult children living with him?

Dont waste your time or others time when you date on the internet. Being true to yourself is perhaps one of the most attractive qualities you can have on your online dating profile. And this will count in the long run when you finally meet your ideal partner.

Nursing Continuing Education Provider – Going Online

Who does not want a job as a registered nurse? Compared to many other jobs, registered nurses are well-paid, respected, and in high demand. In order to obtain the right knowledge and skill to qualify for such jobs, many people are now in the search for a good nursing continuing education provider.

But, have you thought about doing your study online?

Online education provide students with lots of flexibility, and this might be its biggest advantage. Studying online means a student does not have to rearrange their schedule in order to get to a campus at a certain time to take required classes. Transportation also is not a problem. To get to class, all a student has to do is sit down in front of their home computer.

Online education provider do not exercise rigid schedule requirements on students. This is a big advantage for those who have to juggle their nursing studies along with taking care of their homes and children and working at a full time job. In fact, many students in online nursing programs are able to complete their education faster than those in traditional programs. Some are able to earn a degree that usually takes four years in only two.

If you have financial constraint, online continuing education programs have another advantage. Often, studying online is less expensive than enrolling in an on-campus program.

Another bonus is that there are usually no waiting lists when studying online. As more people discover the advantages of becoming a registered nurse, traditional nursing schools are finding it harder and harder to accommodate all who want to enroll. In fact, they are only able to take a limited number of new students at any given time. Which could mean you might find yourself waiting for a spot to open up before you can even begin earning your degree. That usually is not a problem with online continuing education providers.

Finding a good online nursing degree program can be tough. But there are programs being offered by many reputable learning institutions. Some include:

* The University of Phoenix

* Walden University

* Kaplan University

* Vanderbilt University

You may also check CE4U.com as an alternative resource.

So, do you have the passion of becoming a registered nurse? Why not start today by checking for yourself the right nursing continuing education provider. We have discussed the advantages of online providers, and there are truly good ones out there if you do your search.

Are you lonely and bewildered about a relationship breakup and want help to get your ex back

You already know how grueling it is to just wake up and roll out of bed in the morning. You leave your radio off on your way to your job because every song is a painful reminder of him. You can’t even bear to eat at the same restaurants you took her to. And if that isn’t bad enough, you have to deal with the loss of friends and family that are on “their side”. But here’s some good news… Most relationships CAN be salvaged! You may find it difficult to believe that almost every break up for whatever reasonbetrayal, plain old lost passion, loss of interest, a stolen heart and worse…even the worst situations you could conceivelike men serving prison terms have salvaged their relationships. Yes, even Ex-convicts have reunited with girlfriends and wives after being away for years! It doesn’t matter if you were the one that got left or did the leaving your pain is real and can be healed. Find out everything you need to know to feel better within twenty-four hours. It’s true you could be feeling significantly better one day from today. The Magic of Making Up System can… Show you how to take COMPLETE CONTROL OF THE BREAK UP and make your ex become extremely attracted to you and want to have sex with you every day of the week! Yes it is realistic with “The Instant Reconnect Technique” (my favorite technique). You can use these secrets right now to make your ex Come CRAWLING BACK TO YOU on their knees while they are begging you to take them back! However, I must STRONGLY CAUTION YOUthe advice and techniques are VERY unconventional. Relationship counselors get REALLY ANGRY because they are charging a lot of money (sometimes for months and even years) and you could do just one of the procedures in the book And next thing you know… youre back together with your ex. I just don’t believe that any amount of sitting in a classroom can make up for the REAL WORLD experience that you will learn. Human psychology plays a big part in the approach to getting back with an ex. Unconventional techniques and relational psychology is a large part of the Magic of Making Up. It will lead you toward a recovery just like thousands of other separated people have experienced. Your pain could be gone, faster than you can begin to imagine, forever, if youre willing to follow the system. How would it feel to wash away your pain, to remove the knot eating you up from the inside? “Do you want all the magical behavior controlling advice to get your ex back?”

Glendale Outdoor Leadership School

The Glendale Outdoor Leadership School offers a variety of outdoor recreational activities to people in the Spartanburg area. Located in Glendale, South Carolina, the school is a program of the Palmetto Conservation Foundation. The programs goal is to encourage adults and children to lead healthy lifestyles by being active. Some of the activities available at the school include kayaking, fishing, hiking, mountain biking, and climbing.

The school hosts leadership retreats and environmental education seminars. Team building activities and leadership skills are offered to corporations, youth groups, sports teams, and other organizations. Their new Low Challenge Course is a series of activities that help boost team building skills.

The Glendale Outdoor Leadership School is not just open to groups. Individuals can also sign up for classes in indoor rock climbing, paddling, and mountain biking. The schools indoor climbing wall is 20 feet high with more than 1,000 square feet of climbing space. The climbing facility features a bouldering area, crack climbing, and ramped and inverted walls. There are nine belay stations. A climbing assistant is on hand to help during all public climbing sessions. Mountain biking classes are available for riders of all ability levels. Kayaking courses introduce paddlers to the fundamentals of the sport while emphasizing safety. Whether a beginning paddler or one needing a refresher course, participants will quickly gain confidence.

Special Kids Nights are offered on the first Friday of the month from 6-9pm. The kids will enjoy a variety of fun supervised activities such as rock climbing, a nature craft, and games. A snack is included. The cost is $20 for one child with a $5 sibling discount. Glendale Outdoor Leadership School also offers Summer Adventure Camps in June and July for youth 6-15 years of age.

The entire family can enjoy an evening of fun activities on Family Fun Nights, which are scheduled for the second Saturday of each month from 5-8pm. Family members can try indoor rock climbing, team building activities, and a moonlight hike. The evening includes dinner and Smores around the campfire. The cost is $15 for adults and $10 per child. Children must be accompanied by an adult for Family Fun Night. Register ahead of time to reserve a spot.

The Glendale Outdoor Leadership School is located at 270 Wheeling Circle in Glendale, South Carolina, just east of Spartanburg. The facilitys proximity to Lawsons Fork Creek, the Pacolet River, and Croft State Park provides convenient locations to teach courses and practice outdoor skills.